Covalent catalysis involves the substrate forming a transient covalent bond with residues in the active site or with a cofactor.

共价催化涉及底物与活性位点中的残基或与辅因子形成瞬时共价键。

You should check site statistics at least monthly if you have an active site.

如果你有一个活跃的站点，你至少应该每月都查看一下站点的统计表。

Blocks the action of target enzymes by binding nearly irreversibly to their active site.

与附近目标酶的活性位点不可逆的结合。

Preferably, the ligand does not bind to the active site of an endogenous target compound.

优选所述配体不结合内源靶化合物的活性部位。

A mechanism in which the active site of the enzyme does not change shape during catalysis.

一种在催化反应中酶活性位点形状不发生改变的机理。