problems loom large when men don't.

如果人不作为，麻烦会越来越大！

Intellectual property issues also loom large.

知识产权也是一个突出的问题。

Relationships loom large Wednesday noon to Friday eve.

周三中午到周五晚上，关系有点令人忧虑。

But by 2012 the threat posed by deficits will loom large.

但是到2012年，来自财政赤字方面的威胁将放大。

The problems of crime and poverty loom large in many countries.

犯罪和贫困这两大问题在许多国家都很突出。