In no instance have they been seen as the guardians of the liberties of the people.

没有事例表明他们曾作为民众自由的保护人。

In no instance has the virus spread beyond a first generation of close contacts or caused illness in the general community.

在任何情况下，病毒的传播还没有超出第一代密切接触者或在整个社区引发疾病。

Malcolm, for instance, works in isolation but I have no doubts about his abilities.

例如，马尔科姆虽然一个人独立工作，但我丝毫不怀疑他的能力。

I call such issues instance details and I only cover them in these articles on design when in my experience the designer has no choice but to consider them.

我称这类问题为实例细节，在这些文章中，按我的设计经验，只有设计者不得不考虑这类问题时才会触及到。

In particular, there is no information that indicates the location of a particular instance of a service provider.

特别是，不存在任何指示特定服务提供者实例位置的信息。